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Schematic illustration of CCL19’s involvement in cancer development. The tumor-suppressive role of CCL19 (shown in the blue area) relies on the enhancement of anti-tumor responses and inhibition of angiogenesis. In contrast, the tumor-promoting role of CCL19 (shown in the red area) is attributed to the inhibition of cell apoptosis, promotion of metastasis and tumor heterogeneity, and inflammation.
