Table 1.
PMOs
| PMO name | Length | PMO 5′-3′ | % GC | ΔG | No. of ESE peaks covered | % in open conformation | No. of ends in open loop structures |
|---|---|---|---|---|---|---|---|
| hNF1.e17[+70;94] | 25 | GATCCATGGACATTTGACTGGTATT | 40 | −9.6 | 3 | 56 | 1 |
| hNF1.e17[+79;103] | 25 | ATTCTTCATGATCCATGGACATTTG | 36 | −5.15 | 5 | 36 | 2 |
| hNF1.e17[+85;109] | 25 | GTAGTAATTCTTCATGATCCATGGA | 36 | −1.4 | 6 | 28 | 0 |
| hNF1.e17[+108;132] | 25 | CCGGAGAGAGGCTCCAGGAGTACGT | 64 | −8.5 | 8 | 40 | 1 |
| hNF1.e17[+67;94] | 28 | GATCCATGGACATTTGACTGGTATTTCC | 42 | −10.2 | 4 | 50 | 1 |
| hNF1.e17 [+68;95] | 28 | TGATCCATGGACATTTGACTGGTATTTC | 39 | −10.5 | 4 | 50 | 0 |
| hNF1.e17[+69;96] | 28 | ATGATCCATGGACATTTGACTGGTATTT | 36 | −10.5 | 4 | 50 | 0 |
| hNF1.e17[+70;97] | 28 | CATGATCCATGGACATTTGACTGGTATT | 39 | −10.1 | 3 | 50 | 0 |
| hNF1.e17[+76;103] | 28 | ATTCTTCATGATCCATGGACATTTGACT | 36 | −8.4 | 5 | 43 | 2 |
| hNF1.e17[+79;+106] | 28 | GTAATTCTTCATGATCCATGGACATTTG | 36 | −6.4 | 5 | 39 | 1 |
| hNF1.e17[+81;+108] | 28 | CTTCCGGAGAGAGGCTCCAGGAGTACGT | 61 | −8.7 | 5 | 32 | 1 |
| hNF1.e17[+108;+135] | 28 | CTTCCGGAGAGAGGCTCCAGGAGTACGT | 61 | −8.7 | 8 | 43 | 0 |
| hNF1.e17[+115;142] | 28 | CTTTTCCCTTCCGGAGAGAGGCTCCAGG | 61 | −8.3 | 5 | 46 | 1 |