Table 2.
Distribution of NSCLC-SAQ Items, Domains, and Total Score at Baseline
| Items, Domains, Total Score | Response Category, n (%) |
Mean (SD) | Median (Q1–Q3) | Minimum–maximum | ||||
|---|---|---|---|---|---|---|---|---|
| 0, n (%) | 1, n (%) | 2, n (%) | 3, n (%) | 4, n (%) | ||||
| Item 1. Cough | 117 (21.8) | 210 (39.2) | 142 (26.5) | 49 (9.1) | 18 (3.4) | 1.33 (1.02) | 1.00 (1.00–2.00) | |
| Item 2. Pain in chest | 255 (47.6) | 147 (27.4) | 97 (18.1) | 27 (5.0) | 10 (1.9) | 0.86 (1.00) | 1.00 (0.00–1.50) | |
| Item 3. Pain in areas other than chest | 210 (39.2) | 155 (28.9) | 103 (19.2) | 51 (9.5) | 17 (3.2) | 1.09 (1.12) | 1.00 (0.00–2.00) | |
| Item 4. Shortness of breath | 159 (29.7) | 146 (27.2) | 129 (24.1) | 77 (14.4) | 25 (4.7) | 1.37 (1.18) | 1.00 (0.00–2.00) | |
| Item 5. Lack of energy | 113 (21.1) | 143 (26.7) | 158 (29.5) | 95 (17.7) | 27 (5.0) | 1.59 (1.15) | 2.00 (1.00–2.00) | |
| Item 6. Tire easily | 98 (18.3) | 147 (27.4) | 154 (28.7) | 111 (20.7) | 26 (4.9) | 1.66 (1.14) | 2.00 (1.00–3.00) | |
| Item 7. Poor appetite | 237 (44.2) | 99 (18.5) | 100 (18.7) | 63 (11.8) | 37 (6.9) | 1.19 (1.30) | 1.00 (0.00–2.00) | |
| Derived pain domaina | 1.36 (1.11) | 1.00 (0.00–2.00) | 0.00–4.00 | |||||
| Derived fatigue domaina | 1.63 (1.09) | 1.50 (1.00–2.50) | 0.00–4.00 | |||||
| Total scoreb | 6.88 (3.99) | 6.75 (3.50–9.50) | 0.00–18.00 | |||||
Note: N equals 536 (response options for items 1 to 3: 0 = not at all; 1 = mild; 2 = moderate; 3 = severe; 4 = very severe; response options for items 4 to 7: 0 = never; 1 = rarely; 2 = sometimes; 3 = often; 4 = always).
NSCLC-SAQ, NSCLC Symptom Assessment Questionnaire; Q1, first quartile; Q3, third quartile.
a
Derived domains are presented for comprehensiveness and are not intended to be used as an endpoint measure in clinical trials.
b
Total score ranges from 0 to 20 with higher scores indicating more severe NSCLC-related symptomatology.