表 1.

龙杞方治疗DKD KEGG通路富集分析

KEGG pathway enrichment analysis of Longqi Fang against DKD

ID	Description	p.adjust	geneID	Count
hsa04933	AGE-RAGE signaling pathway in diabetic complications	3.14E-05	CASP3/VEGFA/F3/ICAM1/CCL2/VCAM1/PRKCB/COL3A1	8
hsa05418	Fluid shear stress and atherosclerosis	3.14E-05	VEGFA/HMOX1/ICAM1/CCL2/VCAM1/PLAT/NQO1/KDR/HSP90AB1	9
hsa04020	Calcium signaling pathway	0.000253191	VEGFA/EGF/PRKCB/KDR/HRH1/HTR2B/FGF1/MYLK/EDNRA/FLT1	10
hsa04650	Natural killer cell mediated cytotoxicity	0.001273051	CASP3/IFNGR1/ICAM1/PRKCB/SYK/FYN/LCK	7
hsa04510	Focal adhesion	0.002172736	VEGFA/EGF/PRKCB/SPP1/KDR/FYN/MYLK/FLT1	8
hsa05207	Chemical carcinogenesis-receptor activation	0.00243623	VEGFA/EGF/RB1/MYC/PRKCB/AHR/NR1I3/HSP90AB1	8
hsa04066	HIF-1 signaling pathway	0.00243623	IFNGR1/VEGFA/EGF/HMOX1/PRKCB/FLT1	6
hsa04010	MAPK signaling pathway	0.003430192	CASP3/VEGFA/EGF/MYC/PRKCB/KDR/PLA2G4A/FGF1/FLT1	9
sa05219	Bladder cancer	0.003456589	VEGFA/EGF/RB1/MYC	4
hsa01521	EGFR tyrosine kinase inhibitor resistance	0.003588057	VEGFA/EGF/PRKCB/KDR/AXL	5
hsa05167	Kaposi sarcoma-associated herpesvirus infection	0.00549286	CASP3/IFNGR1/VEGFA/RB1/MYC/ICAM1/SYK	7
hsa04614	Renin-angiotensin system	0.007730096	MME/KLK1/CPA3	3
hsa04151	PI3K-Akt signaling pathway	0.008028541	VEGFA/EGF/MYC/SPP1/KDR/SYK/FGF1/FLT1/HSP90AB1	9
hsa05417	Lipid and atherosclerosis	0.008028541	CASP3/CASP1/HSPA5/ICAM1/CCL2/VCAM1/HSP90AB1	7
hsa04370	VEGF signaling pathway	0.008048184	VEGFA/PRKCB/KDR/PLA2G4A	4
hsa04064	NF-kappa B signaling pathway	0.008048184	ICAM1/VCAM1/PRKCB/SYK/LCK	5
hsa04014	Ras signaling pathway	0.010016525	VEGFA/EGF/PRKCB/KDR/PLA2G4A/FGF1/FLT1	7
hsa04668	TNF signaling pathway	0.010016525	CASP3/ICAM1/CCL2/VCAM1/IRF1	5
hsa05164	Influenza A	0.010155883	CASP3/CASP1/IFNGR1/ICAM1/CCL2/PRKCB	6
hsa04726	Serotonergic synapse	0.010155883	CASP3/PRKCB/ALOX5/PLA2G4A/HTR2B	5