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. 2022 Mar 20;12(6):e4354. doi: 10.21769/BioProtoc.4354

Table 4. Minimum required number of p24+ cells for 90% statistical power.

At 90% power, the minimum number of p24+ cells (denominator of 20,000 CD4+ T cells) needed to observe a threshold virus inhibition of 5–30% for 2–6 replicates. The minimum allowed percentage of HIV infection was 0.5%.

Virus inhibition (%)
Number of replicates 5 8 10 15 20 25 30
2 2999 1498 957 397 209 122 100
3 2367 926 632 259 135 100 100
4 1783 738 459 191 100 100 100
5 1559 635 375 159 100 100 100
6 1393 486 314 133 100 100 100