Table 4. Minimum required number of p24+ cells for 90% statistical power.
At 90% power, the minimum number of p24+ cells (denominator of 20,000 CD4+ T cells) needed to observe a threshold virus inhibition of 5–30% for 2–6 replicates. The minimum allowed percentage of HIV infection was 0.5%.
| Virus inhibition (%) | |||||||
| Number of replicates | 5 | 8 | 10 | 15 | 20 | 25 | 30 |
| 2 | 2999 | 1498 | 957 | 397 | 209 | 122 | 100 |
| 3 | 2367 | 926 | 632 | 259 | 135 | 100 | 100 |
| 4 | 1783 | 738 | 459 | 191 | 100 | 100 | 100 |
| 5 | 1559 | 635 | 375 | 159 | 100 | 100 | 100 |
| 6 | 1393 | 486 | 314 | 133 | 100 | 100 | 100 |