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. 2022 Apr 1;107(7):674–680. doi: 10.1136/archdischild-2021-323624

Table 2.

Delphi phase three—important and less important statements for the definition of post-COVID-19 condition

Statement category Statement Important Less important
Three-panel consensus important Two-panel consensus important One or no panel consensus important Three or two-panel consensus unimportant
Testing At least one positive COVID-19 test
A positive PCR test for COVID-19
A positive lateral flow test for COVID-19
An antibody test for COVID-19
Type of initial symptoms Before or at the time of their COVID-19 test
During which time they had at least one recorded fever
During which time they lost their sense of smell
During which time they lost their sense of taste
During which time they had a persistent cough
During which time they had headache
During which time they had unusual tiredness
During which time they had a sore throat
Number of initial symptoms 1 symptom only at the time of testing
2 or more symptoms at the time of testing
3 or more symptoms at the time of testing
4 or more symptoms at the time of testing
5 or more symptoms at the time of testing
Persisting physical symptoms Persisting unusual tiredness
Persisting headaches
Persisting unusual shortness of breath
Persisting loss of smell or taste
Persisting dizziness
1 or more persisting physical symptoms
2 or more persisting physical symptoms
3 or more persisting physical symptoms
4 or more persisting physical symptoms
5 or more persisting physical symptoms
Persisting well-being symptoms A young person experiences difficulties with emotions, concentration, behaviour or not being able to get on with other people
A young person has had persistent symptoms of anxiety (worry)
A young person has had persistent symptoms of low mood (sadness)
A young person has had persistent problems with concentration
The young person’s emotional difficulties have occurred or become worse after COVID-19 infection
Duration Persist for more than 1 month after initial testing*
Persist for more than 3 months after initial testing
Persist for more than 6 months after initial testing
Persist for more than 1 month after initial testing and are from the list of common symptoms on page 4 (ie, unusual tiredness, headaches, shortness of breath, loss of smell or taste, dizziness)
Persist for more than 3 months after initial testing and are from the list of common symptoms on page 4 (ie, unusual tiredness, headaches, shortness of breath, loss of smell or taste, dizziness)
Persist for more than 6 months after initial testing and are from the list of common symptoms on page 4 (ie, unusual tiredness, headaches, shortness of breath, loss of smell or taste, dizziness)
Burden of symptoms The young person has symptoms that continue or develop after COVID-19 which impact their physical, mental or social well-being
The young person has symptoms that are interfering with some aspect of daily living (eg, school, work, home, relationships)
The young person can judge the level of interference with their life themselves
The level of interference is assessed by a professional
The impact of the symptoms on functioning is at least moderate†
Tests to exclude other diseases Persisting COVID-19 antibodies
A negative glandular fever (monospot, antibody or EBV PCR) test†
A normal full blood count
An abnormal full blood count
A normal full blood count, CRP, ESR, urea and electrolytes, creatinine, calcium, liver function tests, random blood glucose†
A normal full blood count, CRP, ESR, urea and electrolytes, creatinine, calcium, liver function tests, random blood glucose, creatine kinase, thyroid function tests, coeliac disease screen, ferritin, vitamin D

Statements closer to three/two-panel consensus important were identified if the percentage of people in each panel rating 7–9 was closer to 70% and 1–3 was closer to <15%.

*Close to three-panel consensus important.

†Close to two-panel consensus important.

CRP, C reactive protein; EBV PCR, Epstein Barr virus polymerase chain reaction; ESR, erythrocyte sedimentation rate.