Table 4:
Predictors of adjuvant treatment delay and omission of adjuvant treatment among patients who survived at least 3 months
| All Stages | FIGO Stage II+ | |||||||
|---|---|---|---|---|---|---|---|---|
| Treatment Delay | No Adjuvant Treatment | Treatment Delay | No Adjuvant Treatment | |||||
| Predictor Variable | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI |
|
| ||||||||
| Race/Ethnicity | ||||||||
|
| ||||||||
| NHW | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| NHB | 1.02 | 0.78–1.33 | 0.96 | 0.84–1.11 | 1.17 | 0.80–1.72 | 1.36 | 1.07–1.72 |
|
| ||||||||
| Hispanic | 1.63 | 1.18–2.25 | 1.16 | 0.95–1.41 | 1.98 | 1.23–3.17 | 1.43 | 1.01–2.03 |
|
| ||||||||
| Surgical Complications | ||||||||
|
| ||||||||
| None | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| 1 | 1.06 | 0.85–1.33 | 1.04 | 0.93–1.16 | 1.08 | 0.76–1.52 | 1.02 | 0.83–1.26 |
|
| ||||||||
| 2 | 1.15 | 0.85–1.55 | 1.09 | 0.94–1.27 | 1.09 | 0.70–1.69 | 1.00 | 0.77–1.29 |
|
| ||||||||
| 3+ | 2.58 | 2.01–3.30 | 1.48 | 1.27–1.73 | 2.69 | 1.87–3.87 | 1.78 | 1.38–2.28 |
|
| ||||||||
| p-trend | <0.001 | 0.001 | <0.001 | 0.004 | ||||
|
| ||||||||
| Age Group | ||||||||
|
| ||||||||
| Ordinal (5 year groups) | 1.01 | 0.99–1.02 | 1.06 | 1.06–1.07 | 1.00 | 0.98–1.03 | 1.11 | 1.09–1.12 |
|
| ||||||||
| Histology | ||||||||
|
| ||||||||
| Endometrioid | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| Non-Endometrioid | 0.88 | 0.74–1.06 | 0.68 | 0.62–0.74 | 0.71 | 0.54–0.95 | 0.62 | 0.52–0.74 |
|
| ||||||||
| FIGO Stage | ||||||||
|
| ||||||||
| I | Ref | Ref | ||||||
|
| ||||||||
| II | 1.00 | 0.78–1.28 | 0.40 | 0.34–0.46 | Ref | |||
|
| ||||||||
| III-IV | 0.60 | 0.49–0.74 | 0.25 | 0.22–0.28 | 0.64 | 0.48–0.84 | 0.63 | 0.53–0.75 |
|
| ||||||||
| Marital Status | ||||||||
|
| ||||||||
| Married or equivalent | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| S/D/W | 1.06 | 0.89–1.27 | 1.14 | 1.04–1.25 | 1.04 | 0.79–1.37 | 1.42 | 1.19–1.70 |
|
| ||||||||
| Comorbidity Score | ||||||||
|
| ||||||||
| None | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| 1 | 1.22 | 0.98–1.52 | 1.08 | 0.97–1.20 | 1.11 | 0.78–1.58 | 1.25 | 1.01–1.55 |
|
| ||||||||
| 2 | 1.33 | 1.04–1.71 | 1.10 | 0.96–1.25 | 1.46 | 1.00–2.14 | 1.35 | 1.06–1.71 |
|
| ||||||||
| 3+ | 1.69 | 1.30–2.20 | 1.46 | 1.27–1.68 | 2.00 | 1.36–2.94 | 1.92 | 1.51–2.45 |
|
| ||||||||
| Surgery Type | ||||||||
|
| ||||||||
| Open | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| MIS | 1.05 | 0.83–1.33 | 1.18 | 1.05–1.32 | 1.21 | 0.81–1.82 | 1.03 | 0.80–1.31 |
|
| ||||||||
| Lymphadenectomy | ||||||||
|
| ||||||||
| Not Done | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| 1–10 nodes examined | 0.93 | 0.74–1.16 | 0.68 | 0.60–0.76 | 1.12 | 0.80–1.56 | 0.89 | 0.72–1.09 |
|
| ||||||||
| >10 nodes examined | 0.73 | 0.59–0.91 | 0.55 | 0.49–0.61 | 0.89 | 0.63–1.24 | 0.74 | 0.60–0.90 |
|
| ||||||||
| Urban Rural Indicator | ||||||||
|
| ||||||||
| All urban | Ref | Ref | Ref | Ref | ||||
|
| ||||||||
| Mostly urban | 1.17 | 0.94–1.44 | 1.23 | 1.10–1.37 | 1.44 | 1.04–2.00 | 1.24 | 1.01–1.53 |
|
| ||||||||
| Mostly rural | 0.82 | 0.56–1.22 | 1.25 | 1.05–1.49 | 0.69 | 0.35–1.34 | 1.24 | 0.88–1.74 |
|
| ||||||||
| All rural | 1.19 | 0.87–1.63 | 1.48 | 1.27–1.74 | 1.83 | 1.19–2.82 | 1.26 | 0.93–1.71 |
|
| ||||||||
| Diagnosis Year (continuous) | 0.95 | 0.93–0.97 | 0.93 | 0.92–0.94 | 0.93 | 0.90–0.96 | 0.94 | 0.92–0.96 |
(Multivariate multinomial logistic regression with receiving adjuvant treatment without delay as referent)
NHW: Non-Hispanic White; NHB: Non-Hispanic Black