Table 1.

Multivariate model exploring PSMA expression with respect to patient/histopathologic characteristics in 50 patients who underwent resection of pulmonary squamous cell carcinoma. Values are presented as n (%) of patients unless otherwise indicated.

Variable	PSMA Staining by Immunohistochemistry
	Tumor Cells					Neovasculature Endothelial Cells
	0	1+	2+	3+		PSMA−	PSMA+
Total (n, %)	11 (22.0)	18 (36.0)	17 (34.0)	4 (8.0)		8 (16.0)	42 (84.0)
Gender
Male (n=33)	8 (24.2)	11 (33.3)	11 (33.3)	3 (9.1)	p=0.923	5 (15.2)	28 (84.8)	p=0.821
Female (n=17)	3 (17.6)	7 (41.2)	6 (35.3)	1 (5.9)		3 (17.6)	14 (82.4)
Age
≤50 (n=6)	2 (33.3)	2 (33.3)	1 (16.7)	1 (16.7)	p=0.986	1 (16.7)	5 (83.3)	p=0.208
51-60 (n=16)	2 (12.5)	6 (37.5)	7 (43.8)	1 (6.3)		1 (6.3)	15 (93.7)
61-70 (n=24)	5 (20.1)	10 (41.7)	8 (33.3)	1 (4.2)		5 (20.8)	19 (79.2)
≥71 (n=4)	2 (50.0)	0 (0.0)	1 (25.0)	1 (25.0)		1 (25.0)	3 (75.0)
Tumor Stage
IA (n=12)	1 (8.3)	7 (58.3)	3 (25.0)	1 (8.3)	p=0.684	1 (8.3)	11 (91.7)	p=0.787
IB (n= 24)	6 (25.0)	7 (29.2)	8 (33.3)	3 (12.5)		6 (25.0)	18 (75.0)
IIA (n=9)	3 (33.3)	2 (22.2)	4 (44.4)	0 (0.0)		1 (11.1)	8 (88.9)
IIB (n=4)	1 (25.0)	1 (25.0)	2 (50.0)	0 (0.0)		0 (0.0)	4 (100.0)
IIIA (n=1)	0 (0.0)	1 (100.0)	0 (0.0)	0 (0.0)		0 (0.0)	1 (100.0)
Smoking History
No (n=5)	2 (40.0)	2 (40.0)	1 (20.0)	0 (0.0)	p=0.083	2 (40.0)	3 (60.0)	p=0.127
Yes (n=45)	9 (20.0)	16 (35.6)	16 (35.6)	4 (8.9)		6 (13.3)	39 (86.7)
Race
White (n=35)	6 (17.1)	15 (42.9)	11 (31.4)	3 (8.6)	p=0.767	4 (11.4)	31 (88.6)	p=0.193
Black (n=11)	4 (36.4)	2 (18.2)	4 (36.4)	1 (9.1)		3 (27.3)	8 (72.7)
Other (n=4)	1 (25.0)	1 (25.0)	2 (50.0)	0 (0.0)		1 (25.0)	3 (75.0)