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. 2022 Apr 5;13:1811. doi: 10.1038/s41467-022-29444-9

Fig. 8. Differential stromal composition of LUAD proteotypes 1 and 3.

Fig. 8

A–C Unsupervised hierarchical clustering of stromal (mouse) proteome does not cluster based on A histological type nor B LUSC proteotypes. C LUAD3 is significantly enriched in stromal proteome cluster (iii) (Fisher’s exact t-test p-value = 3.7E-07). D Significantly differential stromal proteins between LUAD1 and LUAD3 (two-sided t-test, FDR < 0.05). See also Supplementary Data 2. E Significant and active pathways that differ between LUAD1 and LUAD3, based on proteins identified in Fig. 7D. The heatmap shows the gene set score of the pathway for each sample. See also Supplementary Data 2. F Significantly differential pY peptides between LUAD1 and LUAD3 (two-sided t-test, p-value < 0.05).