Table 1.
Characteristics of the included studies and genotype distributions.
| First author | Year | Ethnicity | Country | Sample size | Genotyping method | P for HWE | Source of controls | No. of cases | No. of controls | NOS score | Matched parameters | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | |||||||||||||||
| rs266729 | CC | CG | GG | CC | CG | GG | ||||||||||
| Gupta (36) | 2012 | Asian | India | 137 | 250 | PCR | 0.003 | HB | 77 | 53 | 7 | 156 | 92 | 2 | 7 | Age, Sex, BMI |
| Hashemi (37) | 2013 | Asian | India | 83 | 93 | Tetra ARMS-PCR | 0.107 | PB | 27 | 53 | 3 | 49 | 41 | 3 | 6 | Undetermined |
| Ye (38) | 2014 | Asian | China | 130 | 130 | PCR-RFLP | 0.458 | HB | 77 | 47 | 6 | 83 | 40 | 7 | 7 | Age, Sex |
| Hsieh (39) | 2015 | Asian | Taiwan, China | 350 | 209 | TaqMan | 0.545 | T2DM without NAFLD | 175 | 126 | 49 | 113 | 79 | 17 | 7 | Age, Sex |
| Cheng (40) | 2015 | Asian | China | 338 | 280 | PCR | 0.715 | HB | 158 | 149 | 31 | 164 | 102 | 14 | 7 | Age, Sex, Height |
| Zhang (41) | 2016 | Asian | China | 302 | 310 | PCR-RFLP | 0.619 | HB | 152 | 126 | 24 | 197 | 102 | 11 | 7 | Age, Sex, Drinking, Smoking |
| Zhang (42) | 2016 | Asian | China | 600 | 200 | PCR-RFLP | <0.001 | HB | 180 | 202 | 218 | 143 | 28 | 29 | 7 | Age, Sex, Ethnicity, Birthplace |
| Du (43) | 2016 | Asian | China | 493 | 304 | PCR | 0.068 | HB | 278 | 175 | 40 | 219 | 73 | 12 | 7 | Age, Sex |
| Mahmoud (44) | 2019 | Caucasian | Egypt | 100 | 100 | PCR | 0.539 | HB | 38 | 44 | 18 | 47 | 45 | 8 | 7 | Age, Sex |
| Hasan (45) | 2021 | Caucasian | Egypt | 86 | 86 | PCR-RFLP | 0.236 | HB | 28 | 53 | 5 | 44 | 38 | 4 | 6 | Age |
| rs3774261 | AA | AG | GG | AA | AG | GG | ||||||||||
| Zhang (46) | 2012 | Asian | China | 119 | 350 | PCR-RFLP | 0.808 | PB | 41 | 50 | 28 | 107 | 171 | 72 | 7 | Sex |
| Li (47) | 2015 | Asian | China | 357 | 357 | PCR-RFLP | 0.044 | HB | 48 | 179 | 130 | 131 | 155 | 71 | 7 | Age, Sex |
| Hasan (45) | 2021 | Caucasian | Egypt | 86 | 86 | PCR-RFLP | 0.954 | HB | 11 | 55 | 20 | 39 | 38 | 9 | 6 | Age |
T2DM, diabetes mellitus type 2; NAFLD, nonalcoholic fatty liver disease risk; ARMS, amplification refractory mutation system; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; HB, hospital-based; PB, population-based; BMI, body mass index; HWE, Hardy-Weinberg equilibrium; NOS, Newcastle–Ottawa Scale.