TABLE 3.
Comparison of clinical features of two groups of patients infected by RSV ON1 variants
| Variant 1 | Variant 2 | P value | |
|---|---|---|---|
| Total case number | 44 | 31 | |
| Age (months, mean ± SD) | 24.6 ± 15.8 | 23.5 ± 15.5 | 0.76 |
| Diagnosis | |||
| Acute bronchiolitis/bronchitis | 18 (40.1%) | 11 (35.4%) | 0.74 |
| Bronchopneumonia | 10 (22.7%) | 11 (35.4%) | |
| Viral pneumonia | 16 (36.4%) | 9 (29%) | |
| Clinical manifestations | |||
| Duration of fever (day) | 3.1 ± 2.7 | 2.3 ± 2.4 | 0.24 |
| Hospitalization duration (day) | 5.3 ± 2.1 | 5.5 ± 2.1 | 0.74 |
| Oxygen supplement | 14 (31.8%) | 12 (38.7%) | 0.68 |
| Systemic steroid use | 12 (27.2%) | 11 (35.4%) | 0.31 |
| Bronchodilator use | 24 (54.5%) | 26 (83.8%) | 0.02 |
| Intensive care | 3 (6.8%) | 7 (22.5%) | 0.12 |
| Antibiotics use | 22 (50%) | 14 (45.1%) | 0.11 |
| Laboratory findings | |||
| White cell count (× 104/ul) | 9919.5 ± 4502.6 | 10074.5 ± 4034.3 | 0.87 |
| N/L ratio | 1.8 ± 1.8 | 1.8 ± 2.4 | 0.96 |
| CRP (mg/dl) | 1.3 ± 2.0 | 0.7 ± 1.0 | 0.16 |
Note: Variant 1 featured as E257K substitution. Variant 2 featured as set of K204R/E224A/T238I/Y280H substitutions.
Abbreviations: CRP, C‐reactive protein; N/L ratio, neutrophil/lymphocyte count ratio; RSV, respiratory syncytial virus.