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. 2022 Apr 5;10(4):e004699. doi: 10.1136/jitc-2022-004699

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Timechart of the evolution of tumor size, PD1 +T cells and pembrolizumab plasma concentration after injection, and through the myocarditis event. Thoracic CT-scanner images showing the thymoma 48 days before myocarditis (ie, 34 days before pembrolizumab) and 1-year follow-up after pembrolizumab (maximal tumor size in mm) with the different anticancer treatment’s subsequent sequences. Evolution over time of pembrolizumab circulating levels associated with proportion of T-cells expression PD1 (%) is also represented.