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. 2022 Apr 5;10(4):e004699. doi: 10.1136/jitc-2022-004699

Figure 2.

Figure 2

ICI-myocarditis case report evolution on immunossupressant drugs. Timechart evolution of the patient (103 kg) with the main clinical events, treatments received and abatacept immune-monitoring results (circulating levels and CD86RO). CD86RO, CD86 receptor occupancy on circulating monocytes; (C) ICU, (cardiac). 99th percentile normal upper value of troponin-T was 14 ng/L; Hemodynamic support included extracorporeal life support associated with norepinephrine for the first 48hours. *For graphical representation, negative values of CD86RO were represented as null (see the Methods section for CD86RO value computation). ICI, immune checkpoint inhibitor; ICU, intensive care unit; LVEF, left ventricular ejection fraction; MMF, mycophenolate mofetil.