Figure 2.
ICI-myocarditis case report evolution on immunossupressant drugs. Timechart evolution of the patient (103 kg) with the main clinical events, treatments received and abatacept immune-monitoring results (circulating levels and CD86RO). CD86RO, CD86 receptor occupancy on circulating monocytes; (C) ICU, (cardiac). 99th percentile normal upper value of troponin-T was 14 ng/L; Hemodynamic support included extracorporeal life support associated with norepinephrine for the first 48hours. *For graphical representation, negative values of CD86RO were represented as null (see the Methods section for CD86RO value computation). ICI, immune checkpoint inhibitor; ICU, intensive care unit; LVEF, left ventricular ejection fraction; MMF, mycophenolate mofetil.