TABLE 3.
Bias, MSE, and 95% coverage probability of the proportional treatment effect of 20% (4‐year trial only) for PcLDA with random effects
No Dropout | 10% Annual Dropout | |||||
---|---|---|---|---|---|---|
Sample Size/Arm | Bias | MSE | CP | Bias | MSE | CP |
100 | −0.0041 | 0.0058 | 95.6% | −0.0032 | 0.0084 | 93.8% |
200 | −0.0007 | 0.0028 | 95.2% | −0.0027 | 0.0037 | 94.9% |
300 | −0.0017 | 0.0018 | 96.8% | −0.0027 | 0.0025 | 94.4% |
Bias is the mean of the difference between the estimated parameter and its true value (1000 replicates). Abbreviations: CP, coverage probability of the corresponding 95% confidence interval; MSE; mean of the squared error; PcLDA, proportional constrained longitudinal data analysis model.