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. 2022 Apr 5;8(1):e12286. doi: 10.1002/trc2.12286

TABLE 3.

Bias, MSE, and 95% coverage probability of the proportional treatment effect of 20% (4‐year trial only) for PcLDA with random effects

No Dropout 10% Annual Dropout
Sample Size/Arm Bias MSE CP Bias MSE CP
100 −0.0041 0.0058 95.6% −0.0032 0.0084 93.8%
200 −0.0007 0.0028 95.2% −0.0027 0.0037 94.9%
300 −0.0017 0.0018 96.8% −0.0027 0.0025 94.4%

Bias is the mean of the difference between the estimated parameter and its true value (1000 replicates). Abbreviations: CP, coverage probability of the corresponding 95% confidence interval; MSE; mean of the squared error; PcLDA, proportional constrained longitudinal data analysis model.