Table 2.

Incidence rate ratios for a first deep vein thrombosis, pulmonary embolism, and bleeding after covid-19 using self-controlled case series (SCCS)

Period (days)	Deep vein thrombosis				Pulmonary embolism				Bleeding
	No of events	Incidence rate ratio (95% CI)	P value		No of events	Incidence rate ratio (95% CI)	P value		No of events	Incidence rate ratio (95% CI)	P value
Control period	826	1 (ref)	-		603	1 (ref)	-		4499	1 (ref)	-
Days:
−30 to −4	98	1.39 (1.12 to 1.73)	0.003		157	2.76 (2.29 to 3.33)	<0.001		646	1.58 (1.44 to 1.72)	<0.001
−3 to 0	89	8.71 (6.92 to 10.97)	<0.001		336	39.04 (33.59 to 45.37)	<0.001		305	5.06 (4.48 to 5.71)	<0.001
1 to 7	97	5.59 (4.47 to 6.98)	<0.001		530	36.17 (31.55 to 41.47)	<0.001		357	3.46 (3.09 to 3.87)	<0.001
8 to 14	122	7.44 (6.06 to 9.14)	<0.001		641	46.40 (40.61 to 53.02)	<0.001		267	2.75 (2.42 to 3.13)	<0.001
15 to 30	182	5.31 (4.44 to 6.36)	<0.001		590	20.24 (17.63 to 23.23)	<0.001		378	1.85 (1.65 to 2.06)	<0.001
31 to 60	146	2.59 (2.12 to 3.15)	<0.001		190	4.14 (3.44 to 4.99)	<0.001		501	1.49 (1.35 to 1.65)	<0.001
61 to 90	70	1.42 (1.09 to 1.85)	0.009		96	2.48 (1.95 to 3.15)	<0.001		306	1.06 (0.94 to 1.2)	0.36
91 to 180	131	1.13 (0.91 to 1.41)	0.27		124	1.40 (1.11 to 1.77)	0.005		668	1.07 (0.97 to 1.18)	0.20
Method (days 1 to 30):
SCCS	401	5.90 (5.12 to 6.80)	<0.001		1761	31.59 (27.99 to 35.63)*	<0.001		1002	2.48 (2.30 to 2.68)*	<0.001
Matched cohort study	401	4.98 (4.96 to 5.01)	<0.001		1761	33.05 (32.8 to 33.3)†	<0.001		1002	1.88 (1.71 to 2.07)†	<0.001

CI=confidence interval.

^*Relative incidence (95% CI).

^†Risk ratio (95% CI). 30 day relative risk of same events calculated using adjusted conditional Poisson regression analysis in matched cohort study is shown for comparison.