Table 2.
Pathological characteristics of patients with gastric cancer in each age group
| Group I (young, <65 y) | Group II (early old, 65–74 y) | Group III (old, ≥75 y) | p-valuea) | p-valueb) | |
|---|---|---|---|---|---|
| Number of patients | 1680 | 919 | 384 | ||
| Cancer type | 0.932 | 0.349 | |||
| EGC | 1,219 (72.6) | 644 (70.1) | 270 (70.3) | ||
| AGC | 461 (27.4) | 275 (29.9) | 114 (29.7) | ||
| Lauren histologic type | 0.201 | <0.001* | |||
| Intestinal | 856 (51.0) | 687 (74.8) | 300 (78.1) | ||
| Diffuse | 749 (44.6) | 194 (21.1) | 71 (18.5) | ||
| Mixed | 75 (4.4) | 38 (4.1) | 13 (3.4) | ||
| Tumor location | 0.687 | <0.001* | |||
| Upper | 36 (2.1) | 22 (2.4) | 19 (5.0) | ||
| Middle | 828 (49.3) | 373 (40.6) | 131 (34.1) | ||
| Lower | 816 (48.6) | 524 (57.0) | 234 (60.9) | ||
| Surgical methods | 0.504 | ||||
| Subtotal gastrectomy | 1,325 (78.9) | 712 (77.5) | 300 (78.1) | ||
| Proximal gastrectomy | 66 (3.9) | 31 (3.4) | 18 (4.7) | ||
| Pylorus-preserving gastrectomy | 10 (0.6) | 5 (0.5) | 1 (0.3) | ||
| Total gastrectomy | 279 (16.6) | 171 (18.6) | 65 (16.9) | ||
| Node metastasis | 0.498 | 0.779 | |||
| Negative | 1,245 (74.1) | 689 (75.0) | 281 (73.2) | ||
| Positive | 435 (25.9) | 230 (25.0) | 103 (26.8) | ||
| Cancer stage | 0.273 | 0.471 | |||
| I | 1,310 (78.0) | 711 (77.4) | 291 (75.7) | ||
| II | 225 (13.4) | 129 (14.0) | 51 (13.3) | ||
| III | 112 (6.6) | 66 (7.2) | 34 (8.9) | ||
| IV | 33 (2.0) | 13 (1.4) | 8 (2.1) | ||
| p53 overexpression | 0.099 | 0.004* | |||
| Negative | 1,117 (66.5) | 551 (60.0) | 249 (64.8) | ||
| Positive | 563 (33.5) | 368 (40.0) | 135 (35.2) |
Values are presented as number (%).
EGC, early gastric cancer; AGC, advanced gastric cancer.
a)
Between young-old and old-old groups,
b)
among all age groups.
*
p<0.05.