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. 2022 Mar 23;13:811289. doi: 10.3389/fphar.2022.811289

TABLE 1.

Descriptive presentation of PIs performed with acceptance status entered.

Pharmacist
 Postgraduate pharmacist 1,426 (48.7%)
 Pharmacy resident 1,504 (51.3%)
Prescriber
 Postgraduate physician 802 (27.4%)
 Medical resident 2,128 (72.6%)
Patient gender
 Male 1,421 (48.5%)
 Female 1,509 (51.5%)
Patient age
 ≤59 773 (26.4%)
 60–69 595 (20.3%)
 70–79 569 (19.4%)
 80–89 682 (23.3%)
 ≥90 years 311 (10.6%)
Problem encountered
 Non-compliance with guidelines and contraindications 687 (23.4%)
 Untreated indication 329 (11.2%)
 Underdosing 392 (13.4%)
 Overdosing 559 (19.1%)
 Drug not indicated 203 (6.9%)
 Drug interaction 135 (4.6%)
 Adverse effect 57 (1.9%)
 Inappropriate route and/or administration 267 (9.1%)
 Treatment not received 2 (0.1%)
 Monitoring to be followed 299 (10.2%)
Type of intervention
 Addition 413 (14.1%)
 Discontinuation 497 (17%)
 Substitution/Exchange 358 (12.2%)
 Choice of route of administration 14 (0.5%)
 Therapeutic follow-up 385 (13.1%)
 Optimization of administration modalities 255 (8.7%)
 Dosage adjustment 1,008 (34.4%)
Method of contact
 Verbal 1,623 (55.4%)
 Phone call 455 (15.5%)
 Prescription assistance software 846 (28.9%)
 Paper 6 (0.2%)
Clinical impact on patient health
 None 41 (1.4%)
 Minor 570 (19.5%)
 Moderate 1,317 (44.9%)
 Major 976 (33.3%)
 Vital 26 (0.9%)
Organizational impact
 Unfavorable 89 (3%)
 Nil 2,130 (72.7%)
 Favorable 711 (24.3%)
Economic impact
 Unfavorable 788 (26.9%)
 Nil 1,172 (40%)
 Favorable 970 (33.1%)
ATC class
 A Digestive tract and metabolism 409 (14%)
 B Blood and blood-forming organs 508 (17.3%)
 C Cardiovascular system 272 (9.3%)
 D Dermatological drugs 8 (0.3%)
 G Genitourinary system and sex hormones 33 (1.1%)
 H Systemic hormones, excluding sex hormones 74 (2.5%)
 J General anti-infectives for systemic use 887 (30.3%)
 L Antineoplastics and immunomodulators 68 (2.3%)
 M Muscle and skeleton 37 (1.3%)
 N Nervous system 547 (18.7%)
 P Antiparasitic insecticides 7 (0.2%)
 R Respiratory system 44 (1.5%)
 S Sensory organs 14 (0.5%)
 V Miscellaneous 19 (0.6%)
 Z Drug with no code assigned 3 (0.1%)
PI at reconciliation
 No 2,586 (88.3%)
 Yes 344 (11.7%)
PI using Pharmaclass®
 No 2,786 (95.1%)
 Yes 144 (4.9%)
Validation setting
 Within the pharmacy 1,096 (37.4%)
 Within the ward 1,834 (62.6%)
Care unit
 Nursing home 282 (9.6%)
 Medicine-surgery-obstetrics departments, excluding resuscitation 1,931 (65.9%)
 Resuscitation 717 (24.5%)
Number of drugs per PI
 1 2,349 (80.2%)
 2 499 (17%)
 3 51 (1.7%)
 4 31 (1.1%)