FIGURE 1.

Short term viability/cytotoxicity effects of PBI-05204 with RT in human GBM cell lines. (A) Morphological changes of U87MG and U251 cells cultured with 5.0 μg/ml PBI-05204 with or without RT 4 (Gy) after cells were treated for 72 h. (B–E) Percentage of viable cells from U87MG, T98G, A172 and U251 cell lines, respectively, after treatment with RT alone or RT in combination with PBI-05024 (2.5 and 5.0 μg/ml). Data are presented as mean ± SD of quintuplicate wells. ^a p < 0.01, ^b p < 0.05 PBI-05204 (2.5 μg/ml) + RT vs RT only; **p < 0.01 PBI-05204 (5 μg/kg) + RT group vs RT only.