TABLE 2.
Plasma biomarkers | NC (n = 145) | SCD (n = 50) | MCI (n = 68) | Non-AD dementia (n = 22) | F (P-value) |
Aβ42 (pg/ml) | 9.93 ± 3.01 | 9.30 ± 2.72 | 10.83 ± 2.89 | 11.65 ± 4.41 | 6.02 (0.001) |
Aβ40 (pg/ml) | 183.86 ± 44.15 | 184.61 ± 36.19 | 192.59 ± 52.05 | 209.01 ± 52.52 | 1.93 (0.124) |
Aβ42/Aβ40 (ratio) | 0.0557 ± 0.0172 | 0.0514 ± 0.0139 | 0.0585 ± 0.0200 | 0.0555 ± 0.0144 | 2.10 (0.101) |
T-tau (pg/ml) | 2.50 ± 1.23 | 2.29 ± 0.90 | 2.42 ± 1.00 | 2.32 ± 0.92 | 0.27 (0.844) |
18F-florbetapir PET SUVR | 1.19 ± 0.07 | 1.19 ± 0.07 | 1.17 ± 0.08 | 1.16 ± 0.09 | 0.18 (0.905) |
NC, cognitively normal controls; SCD, subjective cognitive decline; MCI, mild cognitive impairment; AD, Alzheimer’s disease; 18F-florbetapir PET, 18F-florbetapir positron emission tomography; SUVR, standard uptake value ratios. P-values were adjusted for age, sex, and education years with general linear models. The bold values represented the values with statistical significance.