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. 2022 Mar 23;14:832700. doi: 10.3389/fnagi.2022.832700

TABLE 4.

Logistic regression analysis on relationship between plasma biomarkers and AV45 PET positive in different groups.

Plasma Aβ 42 (continuous variable)
Plasma Aβ 40 (continuous variable)
Plasma Aβ 42/Aβ 40 (Z-value)
Group OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
All subjects 0.904 (0.843–0.968) 0.004 1.002 (0.998–1.007) 0.336 0.589 (0.456–0.760) <0.001
NC 0.969 (0.849–1.107) 0.645 1.003 (0.993–1.013) 0.544 0.776 (0.518–1.164) 0.221
SCD 1.308 (1.067–1.602) 0.010 1.025 (1.010–1.041) 0.001 1.095 (0.598–2.003) 0.769
MCI 0.843 (0.727–0.978) 0.024 1.001 (0.993–1.009) 0.770 0.369 (0.192–0.708) 0.003
Dementia 0.828 (0.710–0.966) 0.016 0.990 (0.979–1.001) 0.087 0.261 (0.116–0.586) 0.001

Adjusted for age, gender, and education years. NC, cognitively normal controls; SCD, subjective cognitive decline; MCI, mild cognitive impairment; Dementia, including AD and non-AD dementia. The bold values represented the values with statistical significance.