TABLE 4.
Plasma Aβ 42 (continuous variable) |
Plasma Aβ 40 (continuous variable) |
Plasma Aβ 42/Aβ 40 (Z-value) |
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Group | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value |
All subjects | 0.904 (0.843–0.968) | 0.004 | 1.002 (0.998–1.007) | 0.336 | 0.589 (0.456–0.760) | <0.001 |
NC | 0.969 (0.849–1.107) | 0.645 | 1.003 (0.993–1.013) | 0.544 | 0.776 (0.518–1.164) | 0.221 |
SCD | 1.308 (1.067–1.602) | 0.010 | 1.025 (1.010–1.041) | 0.001 | 1.095 (0.598–2.003) | 0.769 |
MCI | 0.843 (0.727–0.978) | 0.024 | 1.001 (0.993–1.009) | 0.770 | 0.369 (0.192–0.708) | 0.003 |
Dementia | 0.828 (0.710–0.966) | 0.016 | 0.990 (0.979–1.001) | 0.087 | 0.261 (0.116–0.586) | 0.001 |
Adjusted for age, gender, and education years. NC, cognitively normal controls; SCD, subjective cognitive decline; MCI, mild cognitive impairment; Dementia, including AD and non-AD dementia. The bold values represented the values with statistical significance.