Table 3.

Evaluation of the 17-gene Expression Signature Using Whole Gene Expression Data and Principal Components.

Model	AIC	C-index
17 genes	2290	60.0
PC1	2307	54.2
PC1 + PC2	2284	60.9
PC1 + PC2 + PC3	2279	60.7
PC1 + PC2 + PC3 + PC4	2275	61.7
PC1 + PC2 + PC3 + PC4 + PC5	2277	61.5

Bootstrapped c-indexes and Akaike information criteria are provided. Results were obtained from the whole cohort of DLBCL patients treated with R-CHOP (N = 481).

AIC = Akaike information criterion; c-index = concordance index; DLBCL = diffuse large B-cell lymphoma; PC = principal component; R-CHOP = rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone.