Table 5.
Time-dependent AUCs and Brier Scores for the Different Survival Models Within the ABC, GCB, Unclassified and MHG Groups.
| Model | Time (y) | ABC | GCB | Unclassified | MGH | ||||
|---|---|---|---|---|---|---|---|---|---|
| AUC | Brier Score | AUC | Brier Score | AUC | Brier Score | AUC | Brier Score | ||
| 17 genes (PC1 + PC2 + PC3 + PC4) | 0.5 | 64.40 | 0, 069 | 61.42 | 0, 058 | 74.41 | 0, 072 | 53.19 | 0, 106 |
| 17 genes (PC1 + PC2 + PC3 + PC4) | 1 | 58.06 | 0, 162 | 61.37 | 0, 085 | 78.47 | 0, 108 | 49.48 | 0, 245 |
| 17 genes (PC1 + PC2 + PC3 + PC4) | 2 | 56.62 | 0, 216 | 59.18 | 0, 103 | 78.81 | 0, 114 | 58.22 | 0, 264 |
| 17 genes (PC1 + PC2 + PC3 + PC4) | 5 | 53.21 | 0, 252 | 55.81 | 0, 151 | 73.69 | 0, 163 | 56.04 | 0, 287 |
Evaluated time points were 6 mo and 1, 2, and 5 y after diagnosis.
ABC = activated B-cell–like; AUC = area under the curve; GCB = germinal-center B-cell–like; MHG = molecular high-grade; PC = principal component.