Table 2.
Antibiotic concentrations used for BMD and QuickMIC AST testing.
| Antibiotic (#) | Supplier | Article number | Batch number | Concentration range mg/L (QuickMIC) | Concentration range mg/L (BMD) |
|---|---|---|---|---|---|
| Amikacin (AMI)° | Sigma | PHR1860 | LRAB1258 | 1 – 20 | 0.5-32 |
| Cefepime (CEP) | Sigma | PHR1763 | LRAB8503 | 0.5-10 | 0.25-16 |
| Ciprofloxacin (CIP)° | Sigma | PHR1044 | LRAB3671 | 0.125-2.5 | 0.125-4 |
| Colistin (COL) | Sigma | C4461 | 089M4881V | 0.25-5 | 0.125-8 |
| Cefotaxime (CTA)° | Sigma | Y0000420 | 4.0 | 0.25-5 | 0.0156-8 |
| Ceftazidime/(CTZ)° | Sigma | C0690500 | 3 | 0.5-10 | 0.25-16 |
| Avibactam (CTV) | AmBeed | A169351 | A169351-002 | 4* | 4* |
| Gentamicin sulfate (GEN)° | Sigma | G4918 | 028M4827V | 0.5-10 | 0.25-16 |
| Meropenem (MER)° | Sigma | PHR1772 | LRAB7853 | 0.5-10 | 0.25-16 |
| Piperacillin/ | Sigma | PHR1805 | LRAB7665 | 2-40/ | 0.5-64/ |
| Tazobactam (PIT)° | Sigma | 68300 | BCCD0509 | 4* | 4* |
| Tigecycline (TIG) | Sigma | Y0001961 | 1.0 | 0.06-1.25 | 0.0156-2 |
| Tobramycin (TOB)° | Sigma | T1783 | SLBX8043 | 0.5-10 | 0.125-16 |
#Antibiotic abbreviations according to the EUCAST system for antimicrobial abbreviation, available at www.eucast.org.
*For Ceftazidime/avibactam and Piperacillin/tazobactam combinations, the inhibitor was kept at a fixed concentration of 4 mg/L as per EUCAST guidelines.
°Antibiotic included in routine DDM panel at the clinical microbiology laboratory, Uppsala University Hospital.