Table 7.

Comparison of platforms used for performing SARS-CoV-2 detection.

	Point-of-care compatibility	Platforms	Main Physicochemical detection strategy	Other steps needed for complete diagnosis	Typical Setting	Included in assay issued with EUA	Source
Nucleic acids detection	Mostly incompatible	Fully automated equipments	Fluorescence quantification	No	Large, well equiped clinical settings	Yes*	(Nörz et al., 2020)
		PCR equipments	Fluorescence quantification	Eventually, the extraction step	Well equiped to moderate resource settings	Yes*	(Corman et al., 2020)
		Plate readers	Fluorescence quantification	Yes, eventually extraction and amplification step	Moderate resource settings	Yes*	(González-González et al., 2020)
	Generally compatible	Portable PCR equipments	Fluorescence quantification	Eventually, the extraction step	Moderate to low resource settings	No*	(Mendoza-Gallegos et al., 2018)
		Portable Fluorescence readers	Fluorescence quantification	Yes, eventually extraction and amplification step	Moderate to low resource settings	No*	(Ireta-Muñoz and Morales-Narváez, 2020)
		Microfluidics	Fluorescence quantification	Eventually, the extraction step	Moderate to low resource settings	Yes*	(Garneret et al., 2021)
		LFA	Colorimetry	Yes, eventually extraction and amplification step	Moderate to low resource settings	No*	(Xiong et al., 2021)
		Single tube	Fluorescence quantification, or colorimetry	Eventually, the extraction step	Moderate to low resource settings	Yes*	(Arizti-Sanz et al., 2020)

*Retrieved from the instructions for use of approved diagnostic products available in FDA website (https://www.fda.gov/medical-devices/coronavirus-disease-2019-covid-19-emergency-use-authorizations-medical-devices/in-vitro-diagnostics-euas-molecular-diagnostic-tests-sars-cov-2).