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. 2022 Mar 23;13:822615. doi: 10.3389/fphar.2022.822615

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Copyright © 2022 Lu, Wang, Chen, Fan, Zhai, Fang, Cai, Liu, Wu and Cai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Olm plays a positive role in the prevention of SLV-induced lung injury. In addition to its traditional blockage of the renin-angiotensin II system, Olm may play a positive role in the prevention of SLV-induced lung injury through the pulmonary microbiota and metabolites. SLV: single-lung ventilation; Olm: olmesartan.