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. 2022 Mar 30;27(1):31–41. doi: 10.15430/JCP.2022.27.1.31

Figure 2. Mannose alleviated DSS-induced colitis.

Figure 2

(A) Effect of mannose on weight loss rate. Normal mice (Control); Mice treated with 2,000 mg/kg mannose (Man); Mice treated with DSS (DSS); Mice treated with DSS and 1,000 mg/kg mannose (DSS + L Man); Mice treated with DSS and 2,000 mg/kg mannose (DSS + H Man). (B) Effect of mannose on DAI. (C) Representative photos and the length of colon. (D) Representative H&E staining of the colon from each group of mice. (E) Effect of mannose on oxidative stress (GSH, MPO, and LPO). (F) Effect of mannose on the intestinal barrier. Data represent the mean ± standard deviation (n = 10). DSS, dextran sodium sulfate; DAI, disease activity index; GSH, reduced glutathione; MPO, myeloperoxidase; LPO, lipid peroxide. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the DSS group.