Study	Type of diabetes	Duration	No. on LPD	UPD (g/kg/day)	LPD (g/kg/day)	UPD: change in GFR	LPD: change in GFR
Barsotti 1998	Type 1 and 2	3.7 years	32	Not stated	0.3 or 0.7	‐0.9 (0.62)	‐0.22 (0.21)
Barsotti 1988	Type 1	17.4 months	8	1.2‐1.4	<7.5 g/day <4.5 g/day	‐1.38 (0.27)	‐0.03 (0.37)
Brouhard 1990	Type 1	12 months	8	1.0	0.6	‐0.68 (0.4)	‐0.28 (0.15)
Ciavarella 1987	Type 1	4.5 months	7	1.44	45 g/day	‐0.94 (2.19)	3.33 (6.28)
Dullart 1993	Type 1	2 years	14	1.09	0.6	‐0.41 (0.98)	‐0.75 (1.23)
Hansen 2002	Type 1	4 years	38	1.02	0.6	‐0.32 (0.3)	‐0.32 (0.28)
Meloni 2002	Type 1	12 months	15	1.39	0.6	‐0.52 (0.15)	‐0.51 (0.15)
	Type 2	12 months	20	1.39	0.6	‐0.52 (0.15)	‐0.51 (0.13)
Meloni 2004	Type 1 and 2	12 months	40	1.24	0.8	‐0.5 (0.11)	‐0.48 (0.13)
Pijls 2002	Type 2	12 months	63	1.14	0.8	‐0.3 (1.17)	‐0.4 (1.0)
Raal 1994	Type 1	6 months	11	1.6	0.8	‐1.33 (4.5)	0.5 (3.5)
Walker 1989	Type 1	33 months	15	1.13	40 g/day	‐0.53 (0.5)	‐0.13 (0.39)
Zeller 1991	Type 1	37.1 months	20	1.0	0.6	‐1.06 (1.24)	‐0.25 (0.4)
Footnotes
LPD: low‐protein diet
UPD: usual protein diet
GFR: glomerular filtration rate