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. 2007 Oct 17;2007(4):CD002181. doi: 10.1002/14651858.CD002181.pub2

Meloni 2002.

Methods RCT. 
 Duration 12 months.
Participants 32 type 1 patients (14‐32 yrs), duration of diabetes 20.9 years. 
 37 type 2 patients (15‐34 yrs), duration of diabetes 24.9 years. 
 Overt nephropathy and hypertension.
Interventions LPD = 0.6 g/kg/day (n=20). 
 UPD = 1.39 g/kg/day (n=17).
Outcomes GFR. 
 Malnutrition measured by serum albumin, serum pre‐albumin and anthropometric parameters. 
 Compliance monitored by uU. Actual protein intake 0.68 g/kg/day.
Notes Malnutrition noted in LPD.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear