Table 5.

Associations between global metrics of white matter microstructure, DNAm first principal component (left) and gestational age (right)

PS metric	Metric ∼ PC1 DNAm + age at scan + scanner variablea		Metric ∼ gestational age at birth + age at scan + scanner variablea
	β	P	β	P
PSFA	−0.035	0.510	−0.005	0.933
PSMD	0.349	8.37 × 10−10	−0.602	<2 × 10−16
PSNDI	0.364	4.15 × 10−5	−0.594	2.17 × 10−9

^a Scanner variable was included in the model for PSFA and PSMD but not PSNDI because NODDI imaging was carried out for a subset using a single MRI scanner (n = 121). Bold print signifies significant associations.