Table 1.

Demographic and clinical characteristics of 24 patients with osteogenesis imperfecta categorized according to the Sillence classification

Characteristic	Total	Type I	Type Ia	Type Ib	Type III	Type IV	P-value
No. of patients	24	18 (75)	12 (50)	6 (25)	2 (8.4)	4 (16.6)
Age at diagnosis (yr)	10.5±12.5	9.3±12.6	9.4±13.8	9.1±10.9	5.6±7.7	18.3±9.8	0.230
Male sex	14 (58.3)	8 (44.4)	5 (41.7)	3 (50)	2 (100)	4 (100)
Blue sclera	7 (29.2)	15 (83.3)	11 (91.7)	4 (66.6)	0 (0)	1 (25)
Vertebral compression fracture	12 (50)	6 (33.3)	3 (75)	3 (50)	2 (100)	4 (100)
Frequency of fracture per year	3.0±10.0	1.0±0.9	0.9±0.6	1.3±1.4	25.8±34.3	0.5±11.3	0.182
Height-SDS	-1.9±1.8	-1.6±1.5	-1.1±0.9	-2.5±2.1	-3.9±4.0	-2.4±2.2	0.287
Weight SDS	-0.8±1.1	-0.7±1.1	-0.7±1.1	-0.8±1.2	-1.3±1.2	-0.8±1.3	0.848
Lumbar BMD z-score	-1.8±2.4	-0.9±2.2	-0.4±2.3	-3.1±1.6	-4.0±0.5	-3.3±1.9	0.022
Femur neck BMD z-score	-2.9±2.4	-2.9±2.8	-2.5±2.9	-3.8±2.4	-3.1±1.7	-2.9±1.0	0.785
Clinical score	9.7±3.1	8.7±2.5	7.5±1.8	11.0±1.9	16.0±1.4	11.0±1.2	0.003

Values are presented as number (%) or mean±standard deviation.

SDS, standard deviation score; BMD, bone mineral densitometry.