Table 3. Results of Generalized Estimating Equations With Repeated Measurements for Between-Group Differences Regarding Responders and Perceived Recovery Based on a Per-Protocol Analysis.
Characteristic | No./total No. (%)a | OR (95% CI)b | P valuec | |
---|---|---|---|---|
IM injection | IA injection | |||
OMERACT-OARSI responder criteria | ||||
2 wk | 34/68 (50) | 41/65 (63) | 0.8 (0.4-1.8) | .61 |
4 wk | 33/69 (48) | 45/66 (68) | 0.6 (0.3-1.2) | .12 |
8 wk | 36/65 (55) | 37/66 (56) | 1.3 (0.6-2.7) | .45 |
12 wk | 27/67 (40) | 36/65 (55) | 0.7 (0.4-1.6) | .43 |
24 wk | 19/67 (28) | 32/65 (49) | 0.5 (0.2-1.1) | .10 |
Perceived recovery | ||||
2 wk | 41/68 (60) | 50/65 (77) | 0.6 (0.3-1.3) | .18 |
4 wk | 43/69 (62) | 50/66 (76) | 0.6 (0.3-1.3) | .22 |
8 wk | 40/65 (62) | 41/66 (62) | 1.0 (0.5-2.2) | .90 |
12 wk | 31/67 (46) | 37/65 (57) | 0.7 (0.3-1.5) | .35 |
24 wk | 27/67 (40) | 29/65 (45) | 0.9 (0.5-1.9) | .82 |
Abbreviations: IA, intra-articular; IM, intramuscular; OR, odds ratio.
Observed and unadjusted values. There were no missing values in the model covariates, and all patients (138) were included in modeling.
Intra-articular injection as reference; adjusted for baseline Knee Injury and Osteoarthritis Outcome Score pain score, sex, presence of depression, and duration of knee osteoarthritis symptoms. Calculated based on estimated marginal percentages.
P values for superiority tests.