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. 2021 Jul 6;20(3):131–138. doi: 10.18502/cjn.v20i3.7688

Table 4.

Subanalysis of odds ratios (ORs) and 95% confidence intervals (CIs) for neuromyelitis optica spectrum disorder (NMOSD) prevalence through the quartiles of whole grain and legume intake considering neuromyelitis optica immunoglobulin G (NMO-IgG) seropositive and seronegative patients

NMO-IgG seropositive patients
Variable 1 st quartile 2 nd quartile 3 rd quartile 4 th quartile P for trend
Whole grain (g/day) Number of cases/controls 17/25 13/33 1/50 1/56
Model 1* 1 0.37 (0.13-1.06) 0.03 (0.00-0.32) 0.03 (0.00-0.28) < 0.001
Legume (g/day) Number of cases/controls 14/27 8/38 5/49 5/50
Model 1* 1 0.33 (0.10-1.15) 0.10 (0.02-0.40) 0.08 (0.01-0.36) 0.001
NMO-IgG seronegative patients
Variable 1 st quartile 2 nd quartile 3 rd quartile 4 th quartile P for trend
Whole grain (g/day) Number of cases/controls 11/25 9/33 3/50 1/56
Model 1* 1 0.51 (0.16-1.60) 0.15 (0.03-0.65) 0.05 (0.00-0.53) 0.004
Legume (g/day) Number of cases/controls 12/27 8/38 3/49 1/50
Model 1* 1 0.51 (0.15-1.69) 0.11 (0.02-0.54) 0.02 (0.00-0.31) 0.005

NMO-IgG: Neuromyelitis optica immunoglobulin G

*

Regression model adjusted for age, gender, body mass index (BMI), total energy intake, and alcohol consumption