Table 4.
Subanalysis of odds ratios (ORs) and 95% confidence intervals (CIs) for neuromyelitis optica spectrum disorder (NMOSD) prevalence through the quartiles of whole grain and legume intake considering neuromyelitis optica immunoglobulin G (NMO-IgG) seropositive and seronegative patients
NMO-IgG seropositive patients
| |||||||
Variable | 1 st quartile | 2 nd quartile | 3 rd quartile | 4 th quartile | P for trend | ||
Whole grain (g/day) | Number of cases/controls | 17/25 | 13/33 | 1/50 | 1/56 | ||
Model 1* | 1 | 0.37 (0.13-1.06) | 0.03 (0.00-0.32) | 0.03 (0.00-0.28) | < 0.001 | ||
Legume (g/day) | Number of cases/controls | 14/27 | 8/38 | 5/49 | 5/50 | ||
Model 1* | 1 | 0.33 (0.10-1.15) | 0.10 (0.02-0.40) | 0.08 (0.01-0.36) | 0.001 | ||
NMO-IgG seronegative patients | |||||||
Variable | 1 st quartile | 2 nd quartile | 3 rd quartile | 4 th quartile | P for trend | ||
Whole grain (g/day) | Number of cases/controls | 11/25 | 9/33 | 3/50 | 1/56 | ||
Model 1* | 1 | 0.51 (0.16-1.60) | 0.15 (0.03-0.65) | 0.05 (0.00-0.53) | 0.004 | ||
Legume (g/day) | Number of cases/controls | 12/27 | 8/38 | 3/49 | 1/50 | ||
Model 1* | 1 | 0.51 (0.15-1.69) | 0.11 (0.02-0.54) | 0.02 (0.00-0.31) | 0.005 |
NMO-IgG: Neuromyelitis optica immunoglobulin G
Regression model adjusted for age, gender, body mass index (BMI), total energy intake, and alcohol consumption