Table 3.

Validity (AUC, sensitivity, specificity) for NLR, PLR, ALBI, CTP, MELD-Na, and ABR to discriminate the 3 groups

DLC patients (n = 97) vs. compensated cirrhosis patients (n = 20)
	AUC			p			95% CI			Cut-off			Sensitivity			Specificity				PPV			NPV
NLR	0.698			0.005*			0.559-0.836			> 1.942#			82.47			60.0				90.9			41.4
PLR	0.535			0.625			0.408-0.662
ALBI	0.828			< 0.001*			0.726-0.931			> –0.85			76.29			85.0				96.1			42.5
ABR	0.798			< 0.001*			0.695-0.901			≤ 2.667			78.35			75.0				93.2			34.9
CTP score	0.982			< 0.001*			0.963-1.000			> 7#			95.88			90.0				97.9			81.8
MELD-Na	0.745			0.001*			0.616-0.874			> 10.9#			93.81			55.0				91.0			64.7
ALF patients (n = 32) vs. compensated cirrhosis patients (n = 20)
NLR		0.856			< 0.001*			0.748-0.964			> 3.3947#			87.50				75.0			84.8		78.9
PLR		0.681			0.029*			0.528-0.834			> 100.575			71.87				65.0			76.7		59.1
ALBI		0.859			< 0.001*			0.750-0.968			> –0.85			81.25				85.0			89.7		73.9
ABR		0.912			< 0.001*			0.825-0.999			≤ 1.846#			90.62				85.0			90.6		85.0
CTP score		0.946			< 0.001*			0.892-1.000			> 7			84.37				90.0			93.1		78.3
MELD-Na		0.969			< 0.001*			0.930-1.000			> 22			87.50				95.0			96.6		82.6
ALF patients (n = 32) vs. DLD patients (n = 97)
NLR				0.734			< 0.001*			0.635-0.832			> 5.26#			75.0		64.95		41.4			88.7
PLR				0.619			0.044*			0.513-0.725			> 100.19			71.87		50.52		32.4			84.5
ALBI				0.517			0.775			0.403-0.631			> –0.309			50.0		57.73		28.1			77.8
ABR				0.680			0.002*			0.575-0.786			≤ 0.9048			53.13		72.16		38.6			82.4
CTP score				0.637			0.020*			0.515-0.760			≤ 9#			59.38		70.10		39.6			84.0
MELD-Na				0.888			< 0.001*			0.828-0.949			> 21.9			90.62		68.04		48.3			95.7

AUC – area under curve, p value – probability value, CI – confidence interval, NPV – negative predictive value, PPV – positive predictive value, DLC – decompensated liver cirrhosis

*Statistically significant at p ≤ 0.05

^#Cut-off was chosen according to Youden index