Table 1.
Clinicopathological characteristics of 195 patients with rectal cancer according to histological groups
| Variables | SRCC group 18 (100%) | Non SRCC group 177 (100%) | Total 195 (100%) | P-value* |
|---|---|---|---|---|
| Sex | 0.502 | |||
| Male | 13 (72.2) | 130 (73.4) | 143 (73.3) | |
| Female | 5 (27.8) | 47 (26.6) | 52 (26.7) | |
| Age | 0.121 | |||
| Median (range) | 51 (34-63) | 55 (40-68) | 55 (34-68) | |
| PS | 0.315 | |||
| 0 | 7 (38.9) | 42 (23.7) | 49 (25.1) | |
| 1 | 9 (50.0) | 99 (55.9) | 108 (55.4) | |
| 2 | 2 (11.1) | 36 (20.3) | 38 (19.5) | |
| Pre-treatment CEA level (µg/L) | 0.455 | |||
| ≤5 | 8 (44.4) | 95 (53.7) | 103 (52.8) | |
| >5 | 10 (55.6) | 82 (46.3) | 92 (47.2) | |
| Tumor location | 0.264 | |||
| <5 cm | 8 (44.4) | 56 (31.6) | 64 (32.8) | |
| 5-10 cm | 10 (55.6) | 103 (58.2) | 113 (57.9) | |
| 10-15 cm | 0 | 18 (10.2) | 18 (9.2) | |
| Clinical tumor stage | 0.274 | |||
| cT3 | 14 (77.8) | 115 (65.0) | 129 (66.2) | |
| cT4 | 4 (22.2) | 62 (35.0) | 66 (33.8) | |
| Clinical nodal stage | 0.926 | |||
| N0 | 4 (22.2) | 33 (18.6) | 37 (19.0) | |
| N1 | 6 (33.3) | 59 (33.3) | 65 (33.3) | |
| N2 | 8 (44.4) | 85 (48.0) | 93 (47.7) | |
| Stage | 0.753 | |||
| II | 4 (22.2) | 33 (18.6) | 37 (19.0) | |
| III | 14 (77.8) | 144 (81.4) | 158 (81.0) | |
| Histologic grade | 0.347 | |||
| Well | 2 (11.1) | 21 (11.9) | 23 (11.8) | |
| Moderate | 8 (44.4) | 106 (59.9) | 114 (58.5) | |
| Poor | 8 (44.4) | 50 (28.2) | 58 (29.7) | |
| Duration from CTH to Surgery | 0.982 | |||
| Median | 39 days | 37 days | 38 days | |
| Range | (33-51) | (27-56) | (27-56) | |
| Type of surgery | 0.364 | |||
| LAR | 17 (94.4) | 144 (81.4) | 161 (82.6) | |
| APR | 1 (5.6) | 27 (15.3) | 28 (14.4) | |
| Inoperable | 0 | 6 (3.4) | 6 (3.1) |
Abbreviations: CEA: Carcinoembryonic antigen, ECOG PS: Eastern Cooperation Oncology Group Performance Status, CTH: Chemotherapy, LAR: Low anterior resection, APR: Abdominoperineal resection.
*
Chi-square test and Fisher Exact tests were used for all comparisons except age and duration of preoperative chemotherapy (Mann-Whitney U test).