Immune microenvironment of these three groups (IRS/HRS, Mixed, IRR/HRR) in the TCGA dataset. A, B. ssGSEA showed the immune cell proportions of the three groups; C-F. Comparison of the immune score and PD-1, PDL-1, and CTLA-4 levels of the three groups in all patients; G, H. Comparison of HIF-a and CA9 expression levels of the three groups in radiotherapy patients.