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The change of clinical serum marker of renal function in 34 patients with tyrosine-kinase inhibitor (TKI) and administration of programmed cell death protein 1 (PD-1) inhibitor combined treatment. Estimated glomerular filtration rate (eGFR) declined after TKI treatment, while the decrease of eGFR was not significant after administration of PD-1 inhibitor (A). The change of serum creatinine (SCr), blood urea nitrogen (BUN), cystatin C (CYSC) didn’t reach significant level (B-D).
