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. 2021 Nov 15;147(1):98–106. doi: 10.1159/000520674

Table 1.

Recent key RWD publications in HF, ACS, and AF

Data source Participants Findings Reference
Gulf CARE 5,005 patients hospitalized with acute HF ACS was the most common precipitating factor for new-onset HF (39.2%) and non-compliance with medications the most common precipitating factor for decompensated chronic HF (27.8%) [30]

Swedish Heart Failure Registry 21,496 patients with HF Iron deficiency testing only performed in 27% of patients; 49% of those tested had iron deficiency which was associated with recurrent hospitalization [31]

GTWG-Heart Failure Registry 1,551 patients hospitalized for HFrEF and discharged on sacubitril/valsartan and 7,857 discharged on ACEi/ARB Prescription of sacubitril/valsartan was associated with reduced post-discharge mortality and all-cause hospitalization compared with ACEi/ARB [32]

Korean Registry of Acute Myocardial Infarction for Regional Cardio-Cerebrovascular Centres 11,700 patients with acute MI ST-elevation and non-ST-elevation MI occurred in 43% and 57%, with case fatality within 12 months of 10% [33]

EORP-Atrial Fibrillation III Registry 8,306 patients with AF Median age of the registry cohort was 69 years, with patients enrolled across 31 participating countries with future follow-up to assess adherence to guidelines and adverse events [34]

ACEi, angiotensin converting enzyme inhibitor; ACS, acute coronary syndrome; AF, atrial fibrillation; ARB, angiotensin receptor blocker; HF, heart failure; MI, myocardial infarction; RWD, real-world data; Gulf CARE, Gulf aCute heArt failuRe rEgistry; GTWG, Get With The Guidelines; EORP, EUR Observational Research Programme.