Table 1.
Subject characteristics in patients with UC (active group and inactive group) and irritable bowel syndrome (normal control, NC group)
| Group | Active (A) | Inactive (B) | NC (C) | A versus B (p value) | A versus C (p value) | B versus C (p value) |
|---|---|---|---|---|---|---|
| n | 10 | 10 | 10 | |||
| Age, years | 13.3 (10.0–17.5) | 13.3 (9.3–15.3) | 13.2 (10.1–15.7) | N.S. | N.S. | N.S. |
| Sex (M:F) | 5:5 | 3:7 | 4:6 | |||
| Period until UC onset, months | 5.18 (1–15) | 34.4 (5–73) | ||||
| PUCAI | 41.36 (15–75) | 5.5 (0–10) | 0.002 | |||
| WBC, /L | 9,840 (6,400–17,300) | 6,370 (3,900–10,400) | 5,500 (3,700–6,900) | 0.14 | 0.03 | 0.14 |
| CRP, mg/dL | 0.311 (0.0–0.8) | 0.01 (0.0–0.1) | 0.04 (0.0–0.2) | 0.006 | 0.01 | 0.22 |
| ESR, mm | 24.2 (2–51) | 6.8 (2–22) | 6.8 (2–20) | 0.03 | 0.03 | 0.30 |
| FOB, ng/mL | 4,444.6 (945–10,212) | 9.8 (0–53) | 0.6 (0–6) | 0.004 | 0.004 | 0.11 |
| MES | 1.5 (1–2) | 0.1 (0–1) | 0.003 | |||
| Lesion site | ||||||
| Total colitis | 8 | 8 | ||||
| Left-sided colitis | 2 | 2 | ||||
| Treatment | ||||||
| 5-ASA | 0 | 10 | ||||
| Steroids | 0 | 10 |
PUCAI, Pediatric Ulcerative Colitis Activity Index; 5-ASA, 5-aminosalicylic acid; WBC, white blood cell; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; FOB, fecal occult blood; MES, Mayo endoscopic subscore; UC, ulcerative colitis.