Molecular docking of bakuchiol with different targets.

S. no.	Target	Structure	Hydrogen boning with residue	Hydrophobic bonding with residue	Reference
1	DNA polymerase (alpha)		Asp1004	DG111, DC11, Gly958, Tyr865 and Tyr957	35a
2	BthTX-II (2OQD)		Asp48 and Cys44	Gly6, Ala17, Ile18, Tyr21, Tyr27, Gly29, Trp30, and His47	35b
3	Transcriptional activator protein (LasR)		Asp73, Tyr56 and Tyr64	Ala50, Ala 127, Ile52, Leu36, Leu125, Cys79, and Val76	30
4	Estrogen receptor 1 alpha (Esr1)		Glu353 and Arg394	Leu391, Phe404, Leu387, Leu346, Met421, Ile424, Leu525 and Gly521	34
5	Hematopoietic cell kinase (Hck)		Met341	Leu273, Phe278, Val281, Val323, Leu393 and Ala403	35c
6	Mitogen-activated protein kinasep (p38α)		Met109	Val30, Tyr35, Val38, Ala51, Leu75, Ile84, Leu167, and Leu171	35c
7	Tyrosinase inhibitors (2Y9X)		His60	His84, His93, His243, His258, His294, His295, Phe291 and Phe263	35d