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NOR arrangement. A A schematic of the five acrocentric chromosomes in human cells. B A schematic of the organization of the acrocentric p-arm. C A schematic showing that rDNA genes form a head-to-tail tandem array on the acrocentric p-arms. D A schematic of the rDNA transcribed region in human cells. Major pre-rRNA processing sites are indicated. IGS intergenic spacer, ETS external transcribed spacer, ITS internal transcribed spacer
