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| Nucleic acid duplexes | Mean unbinding force (pN) | Mismatch discrimination (pN) | |
|---|---|---|---|
| Full match | Single base mismatch | ||
| DNA–DNA | 124 ± 3 | 105 ± 2 | ∼19 |
| PNA–DNA | 95 ± 2 | 64 ± 1 | ∼31 |
| MO–DNA | 157 ± 2 | 108 ± 1 | ∼49 |
