Kamel 2009.

Methods	RCT. Two parallel groups
Participants	35 participants with generalised myasthenia gravis
Interventions	Group 1 (n = 19) 3 PE before thymectomy Group 2 ( n = 16) no PE before thymectomy
Outcomes	Duration of mechanical ventilation Duration of intensive care unit stay Duration of hospital stay
Notes	RCT aimed at evaluating the effectiveness of pre‐thymectomy plasma exchange
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	No information
Allocation concealment?	Unclear risk	No information
Blinding? All outcomes	High risk	Neither participants nor observers were blinded
Incomplete outcome data addressed? All outcomes	Low risk	No missing outcome data
Free of selective reporting?	Unclear risk	The outcomes are not really specified and therefore impossible to judge
Free of other bias?	High risk	There was no calculation of the sample size necessary for a sufficient power