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. 2022 Feb 28;19(4):1068–1077. doi: 10.1021/acs.molpharmaceut.1c00648

Table 1. Composition of Hydrogenated (h-LNCs) and Deuterated (d-LNCs) LNCs.

excipient composition of h-LNCs (% w/v) composition of d-LNCs (% w/v)
Labrafac lipophile WL 1349 6.2 5.89
octanoic-d15 acid (dC8)   0.17
decanoic-d19 acid (dC10)   0.14
Kolliphor HS 15 4.8 4.8
Phospholipon 90 H 0.4 0.4
sodium chloride 0.5 0.5
Milli-Q water/deuterium oxide (D2O) q.s. q.s.
DF003a 0.19 0.19
a

DF003 is only present in drug-loaded LNCs.