FIG. 5.

Expression time course following exposure to ketoconazole. (A) Culture OD at the times sampled (solid bars, untreated culture; heavily shaded bars, 4 μM ketoconazole; open bars, 8 μM ketoconazole; light shaded bars, 16 μM ketoconazole) and change in TEF1 level as culture goes into saturation (line, average of three measurements of untreated culture in panels B, C, and D; error bars, standard errors). (B through D) Responses of ERG25, YER067W, and YNL300W transcripts (solid symbols) and an internal TEF1 control (open symbols). Culture was left untreated (circles) or treated with ketoconazole at 4 μM (triangles), 8 μM (squares), or 16 μM (diamonds).