TABLE 2.
Function of gene product(s) | Gene(s)a |
---|---|
Involved in protein glycosylation | ALG52,4, ALG3, ALG9, ALG63,3, ALG81,4, ALG10, transferase (PMT family; PMT23,2) CWH41, GLS21,5, MNS1 |
O-glycosylated proteins | AGA1, AGA2, BAR1, CTR1, CTS12,3, CWP1, CWP2, DAN1, FET3, FLO1, FLO5, FLO9, FLO10, FUS1, GAS1, GIT1, HKR1, HSP150, KEX2, KNH1, KRE13,4, KRE92,3, MID2, MSB2, PEX15, PGM1, PGM2, PIR1, PIR3, PRB11,4, SAG1, SEC20, SED1, SED4, SLG1, SRO4, SSR1, STA1, STA2, TIP12,5, TIR13,3, TIR2, YLR110C |
Responsive membrane proteinsb | BAP22,3, BAP30,6, DIP53,4, FET41,7, HNM13,5, HXT10,5, HXT32,4, PHO870,5, RCS11,4, SMF13,4, YDR373W1,4, YGR138C0,5, YKL146W1,4, YNL065W0,6, YNL321W2,3, YOR161C2,3, YOR271C2,4 |
GPI-anchored proteins | AGa1, AGA1, CWP1, CWP2, EGT21,4, FLO1, FLO5, FLO9, GAS1, ICWP, KRE13,4, PRY3, SED1, TIP12,5, TIR13,3, TIR2, YAP3, YCR089W, YDR055W0,5, YDR134C, YDR534C, YEL040W, YER150W0,5, YGR189C, YJR151C, YLR110C, YNL300W3,7, YOR009W, YOR214C |
Involved in synthesis of β-1,6-glucan | CWH53, FKS2, KNR4, HKR1, KRE13,4, KRE5, KRE6, KRE92,3, KRE11, SKN1 |
Osmotic-stress related | |
Part of osmotic-stress response signal pathway | HOG12,3 |
Transcription factor with a role in salt tolerance | CIN51,6 |
Induced by osmotic stress | DDR483,4, DDR2, GRE1, GRE23,4, GRE3, HOT1, PTP2, PTP3, SIP18, SKN7, SKK2, SSK1, STE11, SLN1, SHO1, YPD1 |
Responsive proteins involved in secretionb | VID240,7, RET23,4, SEC170,5, COP12,5, LST83,4, NHX10,5, YGL054C0,6, YHR138C0,5 |
Boldfaced genes were responsive in the study; boldfaced underlined genes had decreased transcript levels. In each superscript, the first number is the number of genetic perturbations (out of a total of three) to which the gene responded and the second is the number of drug treatments to which the gene responded. Lists of genes were obtained from the YPD (18) and from references 4, 9, 15, 16, 17, and 19.
Only responsive genes are shown.