Table 5.

HR of resolution and incident NAFLD according to temporal PA change in BMI change >0 group

	Person-years	Events (No.)	Event rate (per 100,000 person-years)	Age- and sex-adjusted HR (95% CI)	Multivariable-adjusted HR (95% CI)
					Model 1	Model 2	Model 3
Resolution of NAFLD
Inactive→Inactive	18,027.0	407	2.25	1.00	1.00	1.00	1.00
Active or HEPA→Inactive	12,962.8	268	2.06	0.98 (0.84–1.15)	1.04 (0.89–1.22)	1.04 (0.89–1.21)	1.07 (0.91–1.25)
Inactive- → Active or HEPA	9545.3	237	2.48	1.17 (0.99–1.37)	1.17 (0.99–1.37)	1.19 (1.02–1.40)	1.16 (0.99–1.36)
Active or HEPA→Active or HEPA	19,751.9	424	2.14	1.08 (0.94–1.24)	1.12 (0.98–1.29)	1.11 (0.97–1.28)	1.10 (0.96–1.27)
Incident NAFLD
Inactive→Inactive	63,556.4	3448	5.45	1.00	1.00	1.00	1.00
Active or HEPA→Inactive	40,517.9	2617	6.45	0.99 (0.94–1.05)	1.04 (0.98–1.09)	1.03 (0.98–1.08)	0.99 (0.94–1.04)
Inactive- → Active or HEPA	30,474.9	1768	5.80	0.90 (0.85–0.96)	0.91 (0.86–0.96)	0.89 (0.84–0.94)	0.90 (0.85–0.96)
Active or HEPA→Active or HEPA	59,022.7	3821	6.47	0.87 (0.83–0.92)	0.90 (0.86–0.94)	0.89 (0.85–0.94)	0.89 (0.85–0.93)

Model 1: adjustment for age, sex, center, year of screening exam, smoking status, alcohol intake, education level

Model 2: model 1 adjustments plus adjustment for waist circumference

Model 3: model 2 adjustments plus adjustment for waist circumference changes

The reference group was persistently inactive group

Abbreviations: BMI Body mass index, CI Confidence interval, HEPA Health-enhancing physical activity, HR Hazard ratio, NAFLD Non-alcoholic fatty liver disease, PA Physical activity