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. 2022 Apr 6;120:1–11. doi: 10.1016/j.ijid.2022.04.006

Figure 5.

Figure 5

Distribution of CXCR3 and CD4 in colons of patients with COVID-19 with and without diarrhea. Representative fluorescence images (a) and quantification of optical density of CXCR3 and CD4 (b). Panels from left to right: COVID-19-diarrhea (n = 6), COVID-19-nondiarrhea (n = 6), HC (n = 5). “HC” represented Healthy control. Scale bar corresponds to 50 μm. CXCR3 (red), CD4 (green), and nucleus (DAPI; blue). (1-way ANOVA test with Bonferroni post hoc test; n = 5-6 per group) P < 0.05 was considered statistically significant. Error bars denote the mean ± SEM. ns = not significant, * P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001. ANOVA = analysis of variance; SEM = standard error of the mean.