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. Author manuscript; available in PMC: 2022 Apr 6.
Published in final edited form as: Adv Healthc Mater. 2020 Jul 30;9(18):e2000895. doi: 10.1002/adhm.202000895

Table 2:

Selected examples and properties of therapeutics delivered with biomaterials to promote lymphangiogenesis

Therapeutic Biomaterial Carrier Therapeutic
Concentrations
(μg/ml)
Isoelectric
Point
Mass
(kDa)
Hydrodyanmic
Radius (nm)
[138]
ANG-2 Hyaluran/ Methylcellulose 1.0-3.0 [139] 6.7 [140] 1.0 0.7
SDF-1α PLGA 0.4 [141] 9.8 [142] 7.0-8.0 1.5-1.6
VEGF-C Alginate 0.5-2.0 [143]
7.5 x 103 [18]
8.3 [144] 15.5-21.0 2.0-2.3
Fibrin/Collagen 5.0-40.0 [145]
Gelatin 1.0 x 103 [146, 147]
Hyaluran/ Methylcellulose 0.2 [148]
1.0-3.0 [139]
VEGF-D Alginate 0.5-2.0 [143] 6.2 12.0-20.0 1.8-2.2