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. 2022 Mar 23;16:806268. doi: 10.3389/fnins.2022.806268

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Copyright © 2022 Short, Jang, Steiner, Stephens, Girault, Styner and Gilmore.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparing the EBDS neonatal and pediatric atlases. The images are the color-encoded orientation FA maps in axial, sagittal, and coronal slices. The top images are the neonatal atlas, and the bottom images are the pediatric atlas. From the sagittal view, we can observe that the cingulum (CGC) has higher FA due to the greater degree of myelination in the pediatric atlas. Furthermore, given the significantly lower SNR in the neonate DTI, its atlas appears less sharp than the pediatric DTI atlas. Spheres next to the axial view of atlases represent color coding for directional information.