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. Author manuscript; available in PMC: 2022 Apr 6.
Published in final edited form as: Nature. 2019 Aug 15;572(7770):467–473. doi: 10.1038/s41586-019-1492-9

Extended Fig. 10. Rho1-GTP propagation is affected after Rok inhibitor injection:

Extended Fig. 10.

(a) High resolution time-lapse of Rho1-GTP (Anillin(RBD)∷GFP) in a control (water) and an embryo injected with 40mM H-1152 (Rok inhibitor) during propagation. Larger views and later times after injection are shown (compared to Fig.3f). The numbers in yellow indicate cells belonging to cell rows at different distances from the invaginating furrow. N=6 embryos for H-1152 and N=3 for water injections respectively. (b-c) Measurement of Rho1-GTP (Anillin(RBD)∷GFP) mean intensity over time in cells (or regions of cells) at different distances from the invaginating furrow in water (b) and H-1152 (c) injected embryos. Representative of N=47 cells for water and 47 cells for H-1152 injected embryos.